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Proteome Analyst : ウィキペディア英語版 | Proteome Analyst
Proteome Analyst (PA) is a freely available web server and online toolkit for predicting protein subcellular localization, or where a protein resides in a cell.〔 In the field of proteomics, accurately predicting a protein’s subcellular localization, or where a specific protein is located inside a cell, is an important step in the large scale study of proteins. This computational prediction problem is known as Protein subcellular localization prediction. Over the last decade, more than a dozen web servers and computer programs have been developed to attempt to solve this problem. Proteome Analyst is an example of one of the better performing subcellular prediction tools. Proteome Analyst makes predictions for both prokaryotic eukaryotic proteins using a text mining approach.〔 Proteome Analyst was originally developed by the Proteome Analyst Research Group at the University of Alberta, and was initially released on March 2004. It was recently updated on January 2014. ==Input/Output and Method== Users can submit requests to the Proteome Analyst web server by selecting the organism type and then uploading a text file containing the protein sequence in a FASTA format. Proteome Analyst then uses BLAST to look for similar proteins in the Uniprot database with annotation on subcellular localization information. Proteome Analyst then uses a machine-learned classifier to analyze the annotation text fields of the most similar proteins identified in Uniprot search to make the final subcellular localization predictions. Users can view and download Proteome Analyst’s results or ask Proteome Analyst to explain its predictions.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Proteome Analyst」の詳細全文を読む
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